David W Haas Selected Research

Cytochrome P-450 CYP2B6 (CYP2B6)

11/2023	Pharmacogenetics of weight gain following switch from efavirenz- to integrase inhibitor-containing regimens.
10/2021	Efavirenz Pharmacogenetics and Weight Gain Following Switch to Integrase Inhibitor-Containing Regimens.
12/2015	Cost-effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice.
8/2014	Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.
12/2012	Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants.
9/2010	Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study.
7/2006	Human genetic variability and HIV treatment response.

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David W Haas Research Topics

Disease

48	Acquired Immunodeficiency Syndrome (AIDS) 01/2024 - 06/2003
16	Infections 01/2024 - 04/2002
11	HIV Infections (HIV Infection) 01/2024 - 08/2003
9	Tuberculosis (Tuberculoses) 01/2023 - 04/2012
6	Weight Gain 11/2023 - 12/2017
6	Hypersensitivity (Allergy) 01/2017 - 08/2005
6	Peripheral Nervous System Diseases (PNS Diseases) 06/2014 - 08/2005
4	Hyperbilirubinemia 09/2015 - 02/2013
3	Body Weight (Weight, Body) 02/2024 - 11/2004
3	Mitochondrial Diseases (Mitochondrial Disease) 11/2018 - 07/2006
3	Hemochromatosis (Bronze Diabetes) 11/2018 - 07/2006
2	Type 2 Diabetes Mellitus (MODY) 12/2018 - 11/2004
2	Coinfection 01/2015 - 09/2007
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2012 - 12/2009
2	Virus Diseases (Viral Diseases) 12/2010 - 01/2010
1	Substance-Related Disorders (Drug Abuse) 01/2024
1	Genetic Risk Score 01/2023
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2022
1	Persistent Infection 01/2020
1	Hepatitis C 01/2020
1	Frailty 01/2020
1	Cognitive Dysfunction 01/2020
1	Neurocognitive Disorders (Clerambault Syndrome) 01/2019
1	Disease Progression 01/2019
1	Inflammation (Inflammations) 01/2019
1	Drug Hypersensitivity Syndrome 01/2017
1	Jaundice (Icterus) 09/2015
1	Graft vs Host Disease (Graft-Versus-Host Disease) 08/2014

Drug/Important Bio-Agent (IBA)

28	efavirenz (Sustiva)FDA Link 11/2023 - 12/2004
8	Mitochondrial DNA (mtDNA)IBA 01/2021 - 06/2010
8	Atazanavir Sulfate (Reyataz)FDA Link 01/2020 - 11/2004
7	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 11/2023 - 07/2006
6	RNA (Ribonucleic Acid)IBA 02/2024 - 06/2003
6	abacavir (Ziagen)FDA Link 10/2021 - 08/2005
6	Tenofovir (Viread)FDA Link 10/2021 - 08/2013
6	Ritonavir (Norvir)FDA Link 01/2020 - 11/2004
6	Reverse Transcriptase InhibitorsIBA 10/2019 - 08/2005
6	NucleosidesIBA 06/2010 - 08/2005
5	dolutegravirIBA 11/2023 - 12/2017
5	Emtricitabine (Emtriva)FDA Link 01/2021 - 08/2013
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2003
5	Stavudine (Zerit)FDA LinkGeneric 01/2020 - 09/2005
5	Lamivudine (Epivir)FDA Link 01/2019 - 08/2006
5	Nevirapine (Viramune)FDA Link 01/2017 - 08/2005
4	IntegrasesIBA 11/2023 - 12/2017
4	Rifampin (Rifampicin)FDA LinkGeneric 01/2023 - 09/2007
4	Didanosine (Videx)FDA LinkGeneric 01/2020 - 08/2006
4	Zidovudine (Retrovir)FDA LinkGeneric 06/2014 - 08/2006
3	HLA Antigens (Human Leukocyte Antigens)IBA 01/2024 - 12/2010
3	Isoniazid (Ftivazide)FDA LinkGeneric 01/2023 - 01/2021
3	Hemoglobins (Hemoglobin)IBA 01/2022 - 12/2013
3	IronIBA 11/2018 - 07/2006
3	Lopinavir FDA Link 08/2013 - 11/2004
3	Cytochrome P-450 CYP3AIBA 04/2013 - 09/2007
3	Oxidants (Oxidizing Agents)IBA 05/2009 - 12/2003
3	Nelfinavir (Viracept)FDA Link 03/2008 - 12/2005
2	CreatinineIBA 02/2024 - 09/2015
2	Raltegravir Potassium FDA Link 11/2023 - 10/2014
2	Integrase InhibitorsIBA 11/2023 - 10/2021
2	bedaquiline (R207910)IBA 12/2022 - 04/2012
2	rifapentine (Priftin)FDA Link 01/2021 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 12/2018 - 03/2013
2	Peptides (Polypeptides)IBA 01/2017 - 12/2010
2	BilirubinIBA 09/2015 - 04/2014
2	Darunavir (Prezista)FDA Link 10/2014 - 01/2013
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 11/2009 - 10/2003
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 02/2024
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2024
1	HLA-B Antigens (HLA-B)IBA 01/2024
1	EpitopesIBA 01/2024
1	HLA-A Antigens (HLA-A)IBA 01/2024
1	elvitegravirIBA 11/2023
1	Levonorgestrel (Plan B)FDA LinkGeneric 01/2023
1	Genetic Markers (Genetic Marker)IBA 01/2023
1	Clofazimine (Lamprene)FDA Link 12/2022
1	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 01/2022
1	Tuberculin (PPD)IBA 11/2021
1	GoldIBA 11/2021
1	theasinensin AIBA 01/2021
1	tenofovir alafenamideIBA 01/2021
1	etonogestrel (Implanon)FDA Link 01/2020
1	Ethinyl Estradiol (Estinyl)FDA LinkGeneric 01/2020
1	Long Noncoding RNAIBA 01/2019
1	CCR5 Receptors (CCR5 Receptor)IBA 01/2019
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018
1	RacivirIBA 12/2017
1	lamivudine drug combination abacavir FDA Link 12/2017
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2017
1	Dihydrotachysterol (AT 10)IBA 01/2015
1	RifamycinsIBA 01/2015
1	Fibroblast Growth Factor 7 FDA Link 08/2014

Therapy/Procedure

31	Therapeutics 01/2023 - 08/2003
15	Art Therapy 11/2023 - 03/2008
2	Aftercare (After-Treatment) 12/2018 - 02/2006
1	Immunotherapy 01/2024
1	Postcoital Contraception (Emergency Contraception) 01/2023
1	Intramuscular Injections 01/2022
1	Female Contraceptive Devices (Vaginal Ring) 01/2020
1	Duration of Therapy 01/2015
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 08/2014